It is well recognized that there is a decrease in chlorides and an increase in the carbon dioxide-combining power and in the nonprotein nitrogen and the urea nitrogen of the blood in intestinal obstruction. The rôle played by water, when administered by mouth, on the extent of these changes and on length of life has been little studied. A more thorough investigation was thought indicated, particularly since determinations of the chemical composition of the blood are being increasingly used as a guide for treatment of obstruction of the pylorus and small bowel.
In an earlier study of the changes occurring in the blood incident to high intestinal obstruction, the average length of life of dogs was observed.1 These animals were allowed as much water as they wanted, and the average length of life of thirty-five dogs in which the upper part of the jejunum was obstructed was 6.8 days.
CARLSON HE, ORR TG. EXPERIMENTAL OBSTRUCTION OF JEJUNUM: EFFECT OF ADMINISTRATION OF WATER ON LENGTH OF LIFE AND CHANGES IN CHEMICAL COMPOSITION OF BLOOD. Arch Surg. 1934;28(2):292–295. doi:10.1001/archsurg.1934.01170140072003
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