The development of an accurate, harmless method for the visualization of the liver and spleen has been for many years a challenge to the radiologist, internist and surgeon. Information about the size, shape, position, relation and structure of these organs would be of great value in the investigation and interpretation of almost all diseases of the abdominal viscera. If, in addition, it were possible to detect such pathologic conditions as neoplasms, abscesses, malformation, injuries and decreased, increased or abnormal function of these organs, many lives could be saved and much suffering alleviated by earlier and more exact treatment. It is, however, reasonable and necessary to insist that no matter how excellent the diagnostic method, it must not endanger the health or life of the patient.
Progress in the roentgen visualization of the liver and spleen has been made by the intravenous injection of iron preparations, the intravenous injection of dyes
COOKE HH. HEPATOLIENOGRAPHY: EXPERIMENTAL STUDY OF THE ELIMINATION OF THE CONTRAST MEDIUM. Arch Surg. 1934;29(1):29–41. doi:10.1001/archsurg.1934.01180010032004
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