The occurrence of an acanthoma at the anus is sufficiently rare that few observers are privileged to study more than 1 case. In a study of 1,097 cases of malignant tumor occurring in 9,000 consecutive autopsies performed in the Los Angeles County General Hospital, we have had the opportunity to study 3 cases of epidermoid carcinoma which arose in the anorectal region. This constituted an incidence of 1 per cent of all the primary new growths found in the gastro-intestinal tract, and approximately 3 per cent of the carcinomas arising in the large bowel. Lynch1 in a review of 491 cases of cancer of the rectum and pelvic colon reported 15 cases of epithelioma, an incidence of 3 per cent. Pack,2' after an extensive study of anal and rectal neoplasia, concluded that epithelioma in this region was comparatively rare, with an incidence of from 3 to 4 per
HANKINS FD, HARDING WG. ACANTHOMA OF THE ANUS: REPORT OF THREE CASES. Arch Surg. 1934;29(1):77–84. doi:10.1001/archsurg.1934.01180010080010
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