Recent investigations have emphasized the significance of disturbances of the peripheral circulation in the etiology of conditions of the joints and muscles. In 1909, Wollenberg,1 on the basis of arteriosclerotic changes in the affected joints, advanced the theory of the vascular origin of osteo-arthritis; he experimentally produced overgrowth of the patella by a circular ligation of the blood vessels. The experiment was recently repeated and confirmed by Goldhaft2 and his co-workers, who had previously demonstrated, in studies of the blood flow, blood gases, capillary microscopy and surface temperature, a deficiency of peripheral circulation in arthritis. Hench, Henderson, Rowntree and Adson,3 of the Mayo Clinic, reported good results in rheumatoid arthritis with ramisection and sympathetic ganglionectomy, which eliminated the vasoconstriction. Von Papp4 stated that a spasm of the arterioles produces myalgia. The beneficial effect of physical therapy in rheumatic infections is also considered to be due chiefly
KLING DH. TREATMENT OF MYOSITIS, ARTHRITIS AND DISTURBANCES OF THE PERIPHERAL CIRCULATION WITH HISTAMINE BY CATAPHORESIS. Arch Surg. 1934;29(1):138–148. doi:10.1001/archsurg.1934.01180010141016
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