Convalescence after fractures of and operations on bone is prolonged because bone heals more slowly than does soft tissue and because the immobilization required during the process of healing leads to local atrophy of the bone and muscles and to a decrease in the range of motion permitted by the soft tissues of the part. If the union of bone could be hastened and if local atrophy could be prevented considerable economic advantage would result and a proportionately larger number of patients could be treated in orthopedic hospitals each year with the same number of beds. In this article we report a series of clinical experiments in which therapeutic doses of vitamin D and of calcium were administered to normal children receiving an adequate diet in an attempt to hasten union and to prevent local atrophy of bone after stabilizing operations on the feet.
We know of no observations on
FISCHER F, KEY JA. LOCAL ATROPHY OF BONE: III. EFFECTS OF VITAMIN D AND OF CALCIUM ON LOCAL ATROPHY AND UNION. Arch Surg. 1934;29(2):312–315. doi:10.1001/archsurg.1934.01180020144008
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