In the course of detailed studies of the histologic changes in the mammary gland of the rabbit during the growth and sexual cycles certain changes similar to chronic cystic mastitis in man were noted. The entire study will be offered for publication in a special journal. The observations here reported are, however, of sufficient general interest to deserve a wider audience.
Schill1 in the course of a somewhat similar study incidentally mentioned somewhat similar observations. No pathologic interpretation was made.
During the present studies it was found that in the resting stages (i. e., the male breast, the virgin female breast and the resting postlactation breast) the rabbit's breast presents a histologic picture which is in substance identical with the pathologic picture known in the human breast as chronic cystic mastitis. The elements of this picture are: cyst formation, epithelial hyperplasia and metaplasia, mixed cell infiltration, erosion of the
FIFER CL. THE BREAST: I. LESION IN RABBITS RESEMBLING CHRONIC CYSTIC MASTITIS. Arch Surg. 1934;29(4):555–559. doi:10.1001/archsurg.1934.01180040031003
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: