The effects of distention of the urinary bladder on both the bladder itself and on the upper urinary tract have been studied and reported frequently in the past. Unfortunately, each investigator concerned himself with some isolated aspect of the problem, so that a coherent report of the process as a whole remains to be presented. For example, the changes which urethral ligature produces in the bladder, ureters and kidneys are well known. The mechanism by which these changes are produced has, however, remained relatively uncertain. Again, the question of the reflux of bladder urine into the ureters has been almost exhausted both experimentally and clinically; whether this phenomenon occurs in acute retention has been but little investigated. Also, research on the effects of rapid artificial filling of the bladder has led to results diametrically opposed, so far as the behavior of the kidneys and ureters is concerned.
It is the
CREEVY CD. VESICAL DISTENTION: II. EFFECTS ON THE MOTOR MECHANISM OF THE UPPER URINARY TRACT; AN EXPERIMENTAL STUDY. Arch Surg. 1934;29(5):723–740. doi:10.1001/archsurg.1934.01180050028003
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