The case of struma lymphomatosa which is the subject of this report derives its importance from the fact that it was associated with hyperthyroidism in a young woman. The few cases thus far reported have in common the facts that the pathologic entity was found in women over 40, and that it was associated with no thyroid symptoms other than those that might be ascribed to moderate compression of the trachea. Some authors have observed hypothyroidism and myxedema as late effects. A few authors have felt that one could not exclude hyperthyroidism as an insidious precursor to the disease. As far as I can discover, this is the first case to be reported of struma lymphomatosa associated with hyperthyroidism. As such it furnishes an interesting link, perhaps the first stage in the pathogenesis of the obscure thyroid disease known as the struma lymphomatosa of Hashimoto1 or the lymphadenoid goiter
POLOWE D. STRUMA LYMPHOMATOSA (HASHIMOTO) ASSOCIATED WITH HYPERTHYROIDISM: REPORT OF A CASE WITH CLINICAL AND HISTOPATHOLOGIC STUDY. Arch Surg. 1934;29(5):768–777. doi:10.1001/archsurg.1934.01180050073007
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