In a recent paper one of us (F. L. M.)1 presented a clinical and bacteriologic differential diagnosis between certain varieties of acute and chronic infectious gangrene of the skin. One of the chronic forms which was described in that summary was attributed to the pathogenic action of Endamoeba histolytica, but it was pointed out that in the reports of cases which had appeared in the literature no mention had been made of a careful study of the anaerobic organisms present in the lesion and that in many cases the identification of the protozoon present as E. histolytica was open to question. In certain of the cases, to be sure, there was direct evidence and in others circumstantial evidence that E. histolytica was present and was playing a prominent, if not a predominant, rôle in the production and continuation of the disease process.
Recently we have had the opportunity of
MELENEY FL, MELENEY HE. GANGRENE OF THE BUTTOCK, PERINEUM AND SCROTUM DUE TO ENDAMOEBA HISTOLYTICA: REPORT OF A CASE. Arch Surg. 1935;30(6):980–990. doi:10.1001/archsurg.1935.01180120074006
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