Although little attention has been paid to fibro-adenomas of the breast observed during pregnancy and lactation, a study of these lesions is important since the changes seen are frequently confused with changes due to a malignant condition. Especially is such a study of interest in the light of the hormonal relationship of these lesions to the structure and function of the normal breast.
The term fibro-adenoma denotes an encapsulated fibro-epithelial lesion with either the pericanalicular or the intracanalicular type of connective tissue predominant.1 Nineteen cases of fibro-adenoma modified by pregnancy, including 9 of lactating adenoma or so-called cystadenoma (Billroth, 1860; Gross, 1879; Power, 1885; Speese, 1909, and others), have been reported in the literature (McFarland, 1922, 1927; Sudler. 1923; Ingleby, 1932; Cheatle and Cutler, 1931. and others). Several cases reported before 1900 which might properly belong to this group were rejected because the variance in terminology and the lack
MORAN CS. FIBRO-ADENOMA OF THE BREAST DURING PREGNANCY AND LACTATION. Arch Surg. 1935;31(5):688–708. doi:10.1001/archsurg.1935.01180170013002
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