—Mathe and De La Peña35 stated that early diagnosis of primary carcinoma of the ureter affords the only opportunity of cure by early surgical removal. The possibility of this lesion should be considered in patients who have the general symptoms of cancer, who present the triad of hematuria, lumbar pain and tumefaction of the kidney, in whom obstruction of the ureter is encountered and in whom the possibility of the presence of stone, stricture of the ureter and tumor of the kidney can be definitely eliminated. Salient points in establishing a positive diagnosis are: the presence of a tumor projecting from the orifice of the ureter or in the adjacent mucosa, an impassible obstruction in the ureter, modification of the ureteral spurt, nonperistaltic hematuria resulting from attempts to pass with a catheter, and a filling defect of the ureter, as revealed by urogram, with hydro-ureter and hydronephrosis
SCHOLL AJ, JUDD ES, VERBRUGGE J, HEPLER AB, GUTIERREZ R, O'CONOR VJ. A REVIEW OF UROLOGIC SURGERY. Arch Surg. 1936;32(1):163–190. doi:10.1001/archsurg.1936.01180190166009
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