The known and commonly described infections which occur in human beings at the epiphysis or at its union with the diaphysis are as follows:
A. Acute osteomyelitis.
B. Chronic involvement; associated with tuberculosis, syphilis, undulant fever (rare) or actinomycosis (rare).
C. Gradual necrosing lesions of bone the etiology of which is disputed:
1. Köhler's disease of the tarsal navicular bone; 2. Freiberg's disease of the heads of the metatarsal bones; 3. Kienböck's disease of the carpal semilunar bone and many other bones; 4. Koenig's osteochondritis dissecans of the medial condyle of the femur; 5. apophysitis of the os calcis (Sever); 6. aseptic necrosis of the head of the femur, the radius, the humerus or the distal epiphysis of the femur; 7. Osgood-Schlatter's disease of the tibial tubercle; 8. Legg's or Calvé-Perthes' disease, osteochondritis juvenilis.
In this paper it would be impossible to deal with this great variety of diseases about
JOHNSTON RAY. EFFECT OF INFLAMMATION ON THE EPIPHYSES. Arch Surg. 1936;32(5):810–822. doi:10.1001/archsurg.1936.01180230065005
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