[Skip to Content]
[Skip to Content Landing]
Article
November 1936

SPINAL ANESTHESIA: THE EXPERIMENTAL BASIS OF SOME PREVAILING CLINICAL PRACTICES

Arch Surg. 1936;33(5):825-847. doi:10.1001/archsurg.1936.01190050094005
Abstract

The purpose of this report is to examine various clinical practices in the use of spinal anesthesia and the assumption concerning them in the light of facts accumulated in a four year study on experimental spinal anesthesia in the dog. The following topics will be discussed: (1) the effect of the narcotic agent on the respiratory center; (2) the use of narcotics as premedication, (3) the effect of a stimulating drug (a 25 per cent solution of pyridine betacarbonic acid di-ethylamide) on paralysis of the respiratory center, produced by procaine hydrochloride, (4) the fall in blood pressure and its cause, effects and treatment, and (5) the use of carbon dioxide as a stimulant.

EFFECT OF THE NARCOTIC AGENT ON THE RESPIRATORY CENTER  In a previous communication,1 it was shown that if procaine hydrochloride is made to reach the medulla in sufficient strength, either by injection into the cisterna magna

×