In every case acute hematogenous osteomyelitis is basically composed of two components: (a) a general bacterial infection (sepsis, septicemia and bacteremia) and (b) a local lesion in the bone tissue. In the treatment of this disease in the early stages the most important item is the general infection. The ultimate outcome, death or recovery, depends entirely on this factor, and the mortality statistics of acute hematogenous osteomyelitis in its early stages reflects accurately the mortality of general bacterial infection. When divorced from the general bacterial infection and in the absence of any fatal complications or associated lesions, the mortality of the local osseous lesion is nil.
The treatment of a local lesion of the bone is a problem by itself. In the presence of a general bacterial infection, the latter naturally, must be taken into account. In the absence of any demonstrable evidence of a general bacterial infection, the method
WILENSKY AO. ACUTE HEMATOGENOUS OSTEOMYELITIS: CLASSIFICATION OF THE CASES OF ACUTE HEMATOGENOUS OSTEOMYELITIS AS DETERMINED BY THERAPEUTIC INDICATIONS; RESULTS OF OPERATIVE TREATMENT. Arch Surg. 1937;34(2):320–336. doi:10.1001/archsurg.1937.01190080121006
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