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November 1938


Author Affiliations

From the Surgical Pathological Laboratory, Department of Surgery and Gynecology, the Johns Hopkins Hospital and University.

Arch Surg. 1938;37(5):697-725. doi:10.1001/archsurg.1938.01200050003001

The term dysgerminoma was introduced by Meyer to designate a rare type of ovarian tumor formerly referred to by a variety of names—seminoma, embryoma, sex cell carcinoma and large round cell sarcoma. A similar tumor occurring in the testis has been long recognized. Chenot in 1911 first called attention to the corresponding tumor in the ovary, although in this location its occurrence is far more infrequent. Chenot used the name seminoma because he considered the tumor to be derived from the anlage of the seminiferous tubules. Pick in 1912 described such a tumor as chorioepithelioma ectodermale; he concluded that it is teratoid and is derived from the cells of the chorionic villi. Meyer in 1925 made a comprehensive review of all the cases reported in the literature to that date and stressed that this tumor is the most frequent form found in the gonads of hermaphrodites and pseudohermaphrodites. Since

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