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August 1940


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Arch Surg. 1940;41(2):213-220. doi:10.1001/archsurg.1940.01210020009002

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A patient came under my care in December 1939 with acute appendicitis. He presented such a multitude of skeletal tumors that after his recovery from the operation for appendicitis a study was made, and the case was deemed worthy of report. This was not so much because of the rarity of the lesion as because of the number and extent of the tumors, 91 being revealed on the roentgenograms. The condition conformed to the pattern of hereditary deforming chondrodysplasia in that numerous tumors were present, accompanied with skeletal deformities which arose between childhood and maturity and involved bones developed from cartilage. The component parts of each bony system, with the exception of those developed from membrane, showed such involvement.

In addition to the outward projections from the cortical regions giving rise to deformities, inward projections with the formation of central lesions were present. According to Geschickter and Copeland, "the fundamental

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