The feasibility of suturing severed blood vessels has been established by the "auto-hetero" and devitalized vascular transplant work of Carrel and Guthrie1 and has been confirmed by others.2 However, the Carrel-Guthrie technic of end to end anastomosis presents technical difficulties which have discouraged its use except by the surgeon with special training.
It is evident that intravascular thrombosis is the primary factor to be guarded against in vascular anastomosis. Local thrombosis is accelerated by liberation of thromboplastic substance, which, to a large degree, parallels the amount of real trauma to the intima of vessels. The precautions to be observed, therefore, are: 1. Minimize trauma to the vessels, especially to the intima, by delicate handling. 2. Use sutures treated with liquid petrolatum or olive oil (platelets are less apt to stick to oil-soaked sutures),3 and expose a minimum of the suture material to the blood stream. 3. Minimize
SMITH S. A SOLUBLE ROD AS AN AID TO VASCULAR ANASTOMOSIS: AN EXPERIMENTAL STUDY. Arch Surg. 1940;41(4):1004–1007. doi:10.1001/archsurg.1940.01210040193011
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