—MacKenzie1 reported a case in which two separate clinical entities occurred in the same organ; namely, cystic inflammation of the pelvis and ureter and embryonic defect or lack of development that had occurred during intrauterine life.Cystic disease of the urinary tract is primarily a disease of old age, occurring in persons of either sex from whom a history of disturbance or definite inflammation of the urinary tract can be elicited. The condition is reported to have occurred in several cases of double ureter, and, as in MacKenzie's case, it may occur in conjunction with congenital renal hypoplasia.MacKenzie admitted that proliferative renal fibrosis and chronic pyelonephritis with interstitial and glandular degeneration as encountered in his case may be termed "renal atrophy." However, his assumption was that these changes represent secondary atrophy superimposed on hypoplasia, the latter being purely congenital in origin.Smith2 reported 8 cases
SCHOLL AJ, HINMAN F, VON LICHTENBERG A, et al. REVIEW OF UROLOGIC SURGERY. Arch Surg. 1940;41(5):1272–1304. doi:10.1001/archsurg.1940.01210050232015
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