The results of a study of the relation between the duodenal movements and the evacuation of bile into the duodenum in man during fasting have been given in a previous paper. However, in order that the present experimental work may be seen in proper correlation with the previous investigations, a brief outline of the latter will be given. It was found that when the movement of the duodenum was periodic the evacuation of bile was also periodic and that the evacuation occurred only during the active and tetanic periods of duodenal movement and was not seen during the resting period. When the duodenum moved continuously, bile was found in the duodenal drainage in all cases except 1, in which no bile pigment was found, although the duodenum continued active. This brings up the question: What mechanism causes the bile to evacuate periodically and nonperiodically only during the active periods of
UCHIYAMA H, MURAKAMI T. FUNCTIONS OF THE EXTRAHEPATIC BILE DUCTS AND SECRETORY FUNCTION OF THE LIVER: V. EXPERIMENTAL STUDY ON THE RELATION BETWEEN THE MOVEMENTS OF THE DUODENUM AND THE FUNCTIONS OF THE BILIARY TRACT DURING FASTING. Arch Surg. 1941;42(4):703–711. doi:10.1001/archsurg.1941.01210100063006
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