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March 1942


Author Affiliations

From the Division of Surgery, the Mayo Clinic.

Arch Surg. 1942;44(3):520-530. doi:10.1001/archsurg.1942.01210210124008

The morphologic characteristics and the evolution of most gastric ulcers are frequently unpredictable, and hence, in my opinion, most chronic gastric ulcers should be removed surgically without too much delay. After making such a bald statement, I should like to emphasize the fact that some small benign gastric ulcers and occasionally large ones may respond in an amazing fashion to a course of nonsurgical treatment. On the other hand, although many chronic gastric ulcers may seem to respond temporarily to a medical regimen, recurrence of the ulceration is frequent. This recurrence may be a new ulcer or a continuation of the original ulceration which did not heal but merely seemed to, and the recurrent lesion may be even larger and of more rapid growth than the original lesion. During this period, even while the patient has been on more or less of a medical regimen, fairly frequently there has been

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