The most frequent site of cancer in the gastrointestinal tract is the stomach, and, as encountered at the Mayo Clinic, this type of cancer affects males three and a half times as frequently as it affects females. The treatment of cancer of the stomach since Billroth first removed the lesion successfully by gastric resection in 1881 has been removal by surgical methods. Although the results of treatment of localized cancer of the stomach of low grade malignancy have been as satisfactory as those of treatment of cancer of the colon, the greater frequency of highly malignant lesions in the stomach and the large number of cases in which the disease does not produce symptoms indicative of gastric neoplasm until late in the course of the disease explain the larger percentage of inoperable malignant lesions of the stomach as compared with inoperable malignant lesions of the colon. The hopeful aspect of
WALTERS W. MALIGNANT LESIONS OF THE STOMACH. Arch Surg. 1942;44(4):636–650. doi:10.1001/archsurg.1942.01210220039002
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