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July 1942


Author Affiliations

Resident Pathologist; Chief Resident Physician PHILADELPHIA
From the Department of Pathology and the Surgical A Service, Hospital of the Protestant Episcopal Church.

Arch Surg. 1942;45(1):55-73. doi:10.1001/archsurg.1942.01220010058004

Among the strange pathologic curosities are mucocele of the appendix and its even rarer companion, pseudomyxoma peritonaei. We are convinced from conversations with several surgeons that these conditions are more frequently encountered than recognized. When one considers the high percentage of appendixes in which the lining mucosal cells continue to secrete in the presence of a lumen obliterated at some point, one marvels that this combination of circumstances does not result more often in mucous distention of the organ or, as Féré1 in 1876 named the condition, mucocele of the appendix.

Rokitansky,2 in 1842, and Virchow,3 in 1863, were the first to discover mucocele of the appendix and considered it a colloid degeneration of carcinoma. Werth,4 in 1884, first recognized and named the condition known as pseudomyxoma peritonaei. Formerly considered to be exclusively of ovarian origin, it was Fraenkel,5 in 1901, who, observing pseudomyxoma peritonaei

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