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Article
October 1942

CARCINOID TUMOR OF THE APPENDIX: REPORT OF A CASE IN WHICH EXTENSIVE INTRA-ABDOMINAL METASTASES OCCURRED, INCLUDING INVOLVEMENT OF THE RIGHT OVARY

Author Affiliations

Fellow in Proctology, the Mayo Foundation; ROCHESTER, MINN.
From the Division of Surgical Pathology and the Division of Surgery, the Mayo Clinic.

Arch Surg. 1942;45(4):613-622. doi:10.1001/archsurg.1942.01220040109012
Abstract

Review of the literature reveals that whereas carcinoid tumors of the stomach, the small intestine and the colon frequently are classed as being malignant, tumors of an exactly similar nature occurring in the appendix are regarded as being essentially benign. However, recorded instances of no less than 16 metastasizing appendical carcinoids bear witness to the fact that these seemingly innocent neoplasms are capable of widespread dissemination (table). In presenting the following report, we wish to call attention to the manifest malignancy exhibited by the tumor. In addition, the extensive metastatic involvement of the right ovary represents a complication not demonstrated by any other case which we could verify in the literature.

REPORT OF CASE 

Clinical Aspects.  —A married white woman 47 years old registered at the Mayo Clinic on Feb. 18, 1942, complaining of weakness, hematuria and pain in the back of five years' duration.The familial history was essentially

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