DURING the past decade the practical use of venous ligation, anesthesia of the paravertebral lumbar sympathetic system and the anticoagulants has awakened interest in the therapy of deep venous thrombosis. Prior to this period, treatment consisted in rest in bed, elevation of the extremity involved and the application of heat. There has been some confusion in the literature as to the indications for the various types of therapy that are available today. The enthusiasm of various clinics for one of the three therapeutic agents has created a considerable ambiguity in the minds of many physicians as to the benefit derived from the use of any one of them. There does not appear to be any reason for such confusion. None of the three methods, i. e.,, anticoagulant therapy, paravertebral block or venous ligation, is a panacea for venous thrombosis. The application of a few well known and well comprehended physiologic
HOLDEN WD. TREATMENT OF DEEP VENOUS THROMBOSIS WITH REFERENCE TO SUBCUTANEOUS INJECTION OF HEPARIN AND USE OF DICUMAROL. Arch Surg. 1947;54(2):183–187. doi:10.1001/archsurg.1947.01230070188006
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