THAT injuries follow exposure to radium and roentgen rays has been known for many years. In spite of their known hazards, there are still unfortunate end results. Many of these result as incidental by-products in the necessary treatment of deep-seated malignant conditions. Others arise following overzealous treatment of cutaneous lesions that might well have been treated more judiciously by some surgical procedure. Another type of lesion may be seen following treatment by conscientious physicians who have not been trained properly in administration or who are not aware of the potential hazards involved. On the other hand, severe damage may arise following treatment of a person who is unusually susceptible or from the effect of an x-ray machine that has not been properly calibrated. I have been deeply impressed by the observation of patients who seek plastic surgical repair who received roentgen therapy over forty-five years previously, breakdown and carcinomatous degeneration
GREELEY PW. RECONSTRUCTION FOLLOWING IRRADIATION INJURIES. Arch Surg. 1948;56(6):741–749. doi:10.1001/archsurg.1948.01240010752005
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