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April 1950

HETEROTOPIC PANCREATIC TISSUE: Report of a Case Presenting Symptoms of Ulcer and Review of the Recent Literature

Author Affiliations


Arch Surg. 1950;60(4):674-682. doi:10.1001/archsurg.1950.01250010695003

THE TERM "heterotopic pancreatic tissue," currently favored by Barbosa, Dockerty and Waugh1 to describe the condition of an anatomically separate mass of pancreatic tissue in an ectopic position, is not universally adhered to in the literature, which made the recent count of the number of described cases difficult. Although the medical history of this condition reaches back to 1727, when Jean Schultz has been given credit for first having described this condition without the aid of microscopic confirmation,2 and to 1859, when Klob made the first histologic study of 2 cases, it was in 1903 that Magnus-Alsleben3 reported a series of five "adenomyomata" of the stomach and described alveoli of Brunner's glandular, pancreatic and undifferentiated types surrounded by smooth muscle masses, thereby focusing attention on the possibility of a gradation of differentiation of these ectopic masses. In 1909 Gruzdeff4 described an "adenomyoma" which produced clinical symptoms,

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