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January 1951


Author Affiliations

From the Clinical Laboratory, Veterans Administration Hospital.

AMA Arch Surg. 1951;62(1):92-101. doi:10.1001/archsurg.1951.01250030095010

IN THE voluminous literature that has accumulated on the subject of periarteritis nodosa, symptoms referable to the gastrointestinal tract have stood out in bold relief as dominating the clinical picture in this disease. Kussmaul and Maier1 in their original paper regarded the diagnosis of periarteritis nodosa as probable if the clinical symptoms suggested trichinosis in association with nephritis and enteritis. In 1878 Meyer2 suggested the triad of gastrointestinal symptoms, polymyositis and polyneuritis, and chlorotic marasmus as a formula diagnostic of periarteritis nodosa. Harbitz3 in 1927 described six types of periarteritis nodosa, of which the gastrointestinal form was listed first. Libman4 in 1928 mentioned that abdominal symptoms occur frequently in periarteritis nodosa and that a clinical picture of appendicitis may be simulated. Spiegel,5 in a study of 15 cases of periarteritis nodosa, described the usual symptom at onset as abdominal pain. Not infrequently the clinical picture