THIS YEAR marks the 10th anniversary of the inception of the treatment of prostatic cancer by means of the administration of certain estrogenic-like substances, on the one hand, and castration, on the other. Contributions in this field have been many and most valuable, not only in the field of prostatic cancer alone but in the much broader field of the chemical aspects of cancer in general. From all these many contributions and observations has evolved what appears to be a fairly reasonable and rational plan of management. This plan is as follows: First of all, there is no controversy as to whether prostatic cancer should be removed surgically. Our main problem in surgical indications at the present time involves chiefly the extent to which one chooses to perform surgery. It will be quite some time, unfortunately, before an appraisal of end-results will make it possible to determine how radical surgery
HERBST WP. METABOLIC MANAGEMENT OF ADVANCED PROSTATIC CANCER. AMA Arch Surg. 1952;64(6):828–834. doi:10.1001/archsurg.1952.01260010848014
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