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August 1952

CARCINOMA OF THE PANCREAS: Symptoms, Signs, and Results of Treatment in One Hundred Twenty-Two Cases

Author Affiliations

From the Tumor Registry of the Section of Oncology of the Department of Surgery, Yale University School of Medicine.; Dr. Cliffton is Assistant Professor of Surgery (Oncology) Yale University School of Medicine.

AMA Arch Surg. 1952;65(2):290-306. doi:10.1001/archsurg.1952.01260020303012

DEFINITIVE surgical resection of carcinoma of the head of the pancreas or papilla of Vater is relatively recent1 and has been performed so infrequently that the proper evaluation of its place in treatment is difficult. The over-all results of treatment of carcinoma of the pancreas are even more difficult to establish, since most reported series include only cases with resection. Recent reviews by Loggan and Kleinsasser2 and Child3 make redundant a further complete review of the literature.

The incidence of carcinoma of the pancreas is not rare, as established from the 1949 figures of the Connecticut State Tumor Registry.4 It occurred 104 times in 4,661 registered cases, an incidence of 2.2%. The incidence in males was higher, 2.8%, as compared with 1.7% in women. This male-female ratio of 1.6: 1 compares with the 2: 1 and the 2.5: 1 ratio in postmortem series.5 All patients