IN A PREVIOUS paper1 the effects of an overtransfusion of whole blood into the femoral artery in a series of normal dogs were studied. It was found that an intra-arterial transfusion of whole blood equal to 7% of the body weight of the dog, if administered in 30 to 60 minutes, caused the death of 30% of the dogs.
In overtransfusion in 10 normal dogs the femoral venous pressure rose an average of 7 cm. of saline; the respiratory rate rose an average of 14 respirations per minute; the pulse rate fell an average of 60 beats per minute, and the blood pressure tended to fall.
The present study was undertaken to see how a dog with a lowered red blood cell count or lowered plasma proteins would respond to the same sized intra-arterial transfusion of whole blood.
Mongrel dogs weighing about 10 kg. were used. The animals
BEATTIE EJ, KESHISHIAN JM, ADOVASIO D, PIERPONT H, BLADES B, Trams E. EXPERIMENTAL STUDIES WITH INTRA-ARTERIAL TRANSFUSION: Overtransfusion in the Anemic Dog and the Hypoproteinemic Dog. AMA Arch Surg. 1953;66(3):383–385. doi:10.1001/archsurg.1953.01260030398014
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