IN A PREVIOUS paper1 the effects of an overtransfusion of whole blood into the femoral artery in a series of normal dogs were studied. It was found that an intra-arterial transfusion of whole blood equal to 7% of the body weight of the dog, if administered in 30 to 60 minutes, caused the death of 30% of the dogs.
In overtransfusion in 10 normal dogs the femoral venous pressure rose an average of 7 cm. of saline; the respiratory rate rose an average of 14 respirations per minute; the pulse rate fell an average of 60 beats per minute, and the blood pressure tended to fall.
The present study was undertaken to see how a dog with a lowered red blood cell count or lowered plasma proteins would respond to the same sized intra-arterial transfusion of whole blood.
METHODS
Mongrel dogs weighing about 10 kg. were used. The animals