THE ANATOMY of the biliary system has been the subject of extended research for many years. Largely because of their surgical importance in cholecystectomies and the ease with which they may be studied, interest has been centered on the extrahepatic bile ducts, while comparatively little attention has been given to the gross morphology of the bile ducts within the liver.
Prior to 1888, anatomists, other than histologists, directed their attention chiefly to the external morphology of the liver. In that year, Hugo Rex1 made the first attempt to study the intrahepatic course of the vascular and biliary channels by the injection-corrosion method. He investigated the livers of various mammals, including man, but he did not cite the number of human specimens observed, the number probably being very few as judged from the text. It was not until 1924 that a publication appeared which was concerned specifically with the intrahepatic
HEALEY JE, SCHROY PC. ANATOMY OF THE BILIARY DUCTS WITHIN THE HUMAN LIVER: Analysis of the Prevailing Pattern of Branchings and the Major Variations of the Biliary Ducts. AMA Arch Surg. 1953;66(5):599–616. doi:10.1001/archsurg.1953.01260030616008
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.