THE THERAPEUTIC management of malignant soft-tissue tumors of the extremities may be simple and uncomplicated but also may become a most difficult and perplexing situation, particularly when the tumor has approached the border line of curability by metastasizing to the regional lymph nodes. There seems to be no unanimity of opinion as to the ideal therapeutic methods that should be utilized when such a situation is encountered. This is in distinct contrast to the uniformity of thought on the management of the primary tumor as well as the associated lymph-node-bearing area in certain other regions of the body. Treatment of carcinoma of the breast, for example, until recent years at least, was a generally accepted, uniform surgical exercise, as was also the treatment of carcinomas in various locations of the large intestine, with the possible exception of the rectum. The standardization of extensive surgical procedures for the management of cancer
LAWRENCE EA, DICKEY JW, VELLIOS F. MALIGNANT TUMORS OF THE SOFT TISSUES OF THE EXTREMITIES. AMA Arch Surg. 1953;67(3):392–401. doi:10.1001/archsurg.1953.01260040399011
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