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October 1953

ADEQUATE BREAST BIOPSY: Experience in One Thousand Consecutive Personal Cases

Author Affiliations

From the Samuel D. Gross Surgical Division of the Jefferson Medical College of Philadelphia and the Jefferson Medical College Hospital.

AMA Arch Surg. 1953;67(4):526-536. doi:10.1001/archsurg.1953.01260040535006

EARLIER diagnosis of breast cancer demands constant reconsideration and expansion of all available measures. Periodic self-examination of the breast, coupled with periodic examination by the physician, is the established first step. In the next step, the clinical evaluation of the lesion with respect to biopsy, the physician is confronted with the temptation of "watchful waiting." This pitfall can be overcome only by prompt biopsy of any area in the breast that varies from the surrounding tissue. It is the purpose of this paper to discuss our concept of adequate breast biopsy, its indications, its technique, and the results obtained in 1,000 consecutive personal cases during the past 10 years.

INDICATIONS FOR BIOPSY  Our concept of adequate breast biopsy is one in which sufficient tissue is removed to reveal the presence of any obvious or occult cancer by immediate thorough pathologic examination (Table 1). Despite the easy accessibility of the breast

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