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October 1954


AMA Arch Surg. 1954;69(4):533-539. doi:10.1001/archsurg.1954.01270040089014

WITH REPORTS of possible cures or prolonged remission of periarteritis nodosa with cortisone or corticotropin therapy, the early diagnosis of the disease becomes of greater significance. Either there is an increase in the frequency of the disease, or the increased awareness of the disease is resulting in more frequent diagnoses. Although the collagen diseases remain poorly understood, some progress is being made as the clinically benign forms of the disease are being separated from the severer forms.2 This progress may be enhanced by additional case reports of clinical and pathological findings.

The surgeon is interested in this disease from several standpoints. The gastrointestinal tract is involved by this disease in 50 to 56% of the cases.* Hematemesis or melena occur in 18% of the cases. It should, therefore, be considered in the differential diagnosis of other surgical diseases of the abdomen. It is frequently the surgeon who is initially