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July 1955

Benign Cystic Islet-Cell Tumor of the Head of the Pancreas: Report of a Case Probably of Delta-Cell Origin

Author Affiliations

Bombay, India; St. Louis
From the Department of Pathology and the Division of Surgery, The Jewish Hospital of St. Louis, and the Department of Surgery, Washington University School of Medicine.

AMA Arch Surg. 1955;71(1):74-77. doi:10.1001/archsurg.1955.01270130076012

In the course of a study dealing with pseudocysts of the pancreas reported by one of us (J. G. P.),1 a case was encountered which presented clinical characteristics simulating an inflammatory cyst but which on pathological examination proved to be an unusual neoplastic lesion of the pancreas. This tumor showed cytological characteristics consistent with an islet-cell tumor, probably of delta-cell origin, as reported by Sailer and Zinninger,2 but with the added unusual feature of cystic degeneration. This case is reported here because of its unusual pathological nature and because of certain clinical considerations which warrant discussion.

REPORT OF A CASE  A 61-year-old white woman was admitted to the Jewish Hospital in June, 1953, because of weakness, loss of appetite, loss of 25 lb. over a period of about one month, and passage of dark urine. There was no history of hematemesis, icterus, diarrhea, or bloody or tarry stools.

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