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July 1956

Perforation of Duodenal Ulcer and Rupture of StomachReport of Two Cases in Newborn Infants with Survival Following Closure

AMA Arch Surg. 1956;73(1):179-182. doi:10.1001/archsurg.1956.01280010181024

According to the reported cases, perforation of a peptic ulcer and rupture of the stomach are rare entities in infancy, inasmuch as only 30 such cases have been reported up until the end of 1954.1

Peptic ulceration in infants and children, including perforation, was reviewed by Holt in 1913. Bird, Limper, and Mayer reported2 33 cases of perforation in a total of 245 cases of peptic ulcer in infants and children from 17 days to 15 years of age. Other summaries are those of Guthrie,3 Hollander and Stark,4 McAleese and Sieber,5 and Hutchins.6 The earliest perforated peptic ulcer in infancy to be treated surgically with recovery was that in a 34½-hour-old baby reported by Bird and co-workers.2 Lee and Wells described9 a perforation of an ulcer in utero and numerous authors have reported perforations of duodenal ulcers in infants in the first

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