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August 1956

Plasma Volume Determinations in the Evaluation of the Surgical Patient

Author Affiliations

From the Department of Surgery, University of Illinois College of Medicine, and the Illinois Research and Educational Hospitals.; Evans blue dye was generously supplied by the Medical Department, Division of Warner-Hudnut, Inc., New York.

AMA Arch Surg. 1956;73(2):353-361. doi:10.1001/archsurg.1956.01280020167030

Although plasma volume determinations have been advocated by many clinicians to be of use in the evaluation of surgical patients preoperatively and postoperatively, their use has not been widespread. There are perhaps several reasons for this, but we believe the most important one is the fact that there has not been enough emphasis placed upon their specific use and value for the individual patient. At the same time there appear to be certain misunderstandings in regard to the use as well as the limitations of plasma volume determinations which have contributed somewhat to the lack of confidence in this laboratory procedure.

It has been shown that study of the plasma and blood volumes in chronically ill patients reveals general changes from the values of health when groups are studied as a whole,1 and, although it cannot be denied that these studies have advanced our knowledge and understanding of the