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Original Article
April 1957

Dioctyl Sodium Sulfosuccinate (Colace) Following Proctologic Operations

AMA Arch Surg. 1957;74(4):610-614. doi:10.1001/archsurg.1957.01280100128023

Introduction  The proctologic aspects of constipation were presented from a broad biologic standpoint at a symposium on the normal and abnormal physiology and therapeutics of the colon held by the Section of Biology of the New York Academy of Sciences on May 8 and 9, 1953.1 Lesions such as diverticulitis, complete and incomplete colonic obstruction, megacolon and other congenital colonic and anorectal malformations, anal fissure, so-called "pectinosis," hemorrhoids, prolapse, and megarectum were discussed briefly. It was then stated that "laxatives have no place in the therapy of constipation caused by organic etiologic factors." Although functional constipation, or constipation on a habit basis, hardly belongs in the realm of the proctologist, I nevertheless stated that with Ogilvie I believe that "in the absence of organic causes, normal defecation usually 'comes from equanimity and common sense.' Hardly ever do I find a need for cathartic drugs in the management of the