Cancers arising in the laryngopharynx, extrinsic larynx, and upper cervical esophagus constitute difficult therapeutic problems. The main method of treatment in the past has been irradiation therapy. A survey based on reports from eight different world radiation centers1 indicates that, when total experiences are reported, the "world cure rate" is found to vary from a low of 3% to a high of 14% with a mean figure of 7.6% (Table 1). Cancer therapists are now turning with greater frequency to surgery to improve these results. With the surgical advances of the last two decades, it is now possible to perform the extensive operations required for extirpation of these tumors with a reasonable morbidity and mortality. Preliminary reports from centers dealing with these operations indicate an improvement in both the over-all survival figures and the palliation received when compared with irradiation.
Physiologically, patients will tolerate almost any degree of soft-tissue
MORFIT HM, KLOPP CT, NEERKEN AJ. Bridging of Laryngopharyngeal and Upper Cervical Esophageal Defects: Use of Artificial Materials. AMA Arch Surg. 1957;74(5):667–674. doi:10.1001/archsurg.1957.01280110009002
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