The rarity of primary carcinoma of the appendix has been pointed out by most authors writing on the subject. Consequently, general surgical textbooks make scant reference to the condition, and any large series studied of necessity has to be taken from the surgical literature. Few cases, indeed, occur in the surgical experience of one person, and these are usually published as isolated case reports because of their rarity. For this reason, also, statistical studies on the frequency of occurrence of these appendiceal tumors are in most instances inaccurate.
There are no pathognomonic signs or symptoms of primary carcinoma of the appendix. It has been pointed out that with appendiceal neoplasms the clinical signs may be noteworthy by their absence, often despite large tumor growths. Even when dealing with a symptom-producing tumor, the physician is rarely able to establish a correct diagnosis before operation, and the operating surgeon may share in
RABINOVITCH J, RABINOVITCH P, ROSENBLATT P, ZISK H. Primary Carcinoma of the Appendix: An Incidental Finding During Laparotomy. AMA Arch Surg. 1957;75(1):122–127. doi:https://doi.org/10.1001/archsurg.1957.01280130128022
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