Malignant neoplasms of the small intestine are rare, comprising 1%-3% of those occurring in the gastrointestinal tract.2 Malignant tumors of the jejunoileum are twice as frequent as the benign type.3 One case of every 15 or 20 cases in the malignant group is a carcinoid.1 Ariel4 reports an incidence of 8.3% of carcinoid in his series of resected neoplasms of the small intestine. Carcinoids of the small intestine are frequently an incidental finding at surgery or autopsy.
Dockerty5 and Foreman6 believe the ileum to be the commonest site of extraappendiceal carcinoid, whereas Hines, Hanley, and Boese7 and Mrazek, Godwin, and Mohardt8 report rectal lesions to be the commonest extraappendiceal source. Of small intestinal carcinoids, 24.9% metastasize, but appendiceal carcinoid usually does not.4
Carcinoid of the small intestine produced symptoms in about 36% of the cases and, when symptomatic, was associated with
MANN LS, SIMPSON RD. Carcinoid of the Ileum: Unusual Cause of Gastrointestinal Bleeding. AMA Arch Surg. 1957;75(1):161–164. doi:https://doi.org/10.1001/archsurg.1957.01280130167033
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: