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August 1957

Malignant Brenner Tumor

Author Affiliations

Rochester, Minn.
Fellow in Obstetrics and Gynecology, Mayo Foundation (Dr. Mackinnon). Section of Surgical Pathology, Mayo Clinic and Mayo Foundation (Dr. Dockerty). The Mayo Foundation, Rochester, Minn., is a part of the Graduate School of the University of Minnesota.

AMA Arch Surg. 1957;75(2):282-286. doi:10.1001/archsurg.1957.01280140120022

The malignant Brenner tumor is an unusually rare lesion, and thus far only six cases have been reported in the literature. Forty-two cases of Brenner tumor were reported from the Mayo Clinic in 1950, all of which were benign.1 However, a malignant Brenner tumor was seen in 1954. A report of this case is presented herewith.

Report of Case  A 59-year-old white woman (sextigravida, quadripara, two abortions) was first seen at the Clinic in 1938 because of symptoms referable to a duodenal ulcer. Pelvic examination at this time revealed a leiomyoma in the uterus 3 to 4 cm. in diameter.In 1954 the patient returned, complaining of lower abdominal enlargement of two weeks' duration. She reported that the menopause had occurred in 1947. On examination a firm, somewhat nodular mass was found in the left adnexal region. Abdominal hysterectomy and bilateral salpingo-oophorectomy were carried out.The uterus was not

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