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October 1957

Carcinoma of the Breast: Extent of Original Disease Related to End-Results

Author Affiliations

Louisville, Ky.
From the Department of Surgery, University of Louisville School of Medicine.; Former Fellow in Surgery, the American Cancer Society and the National Cancer Institute (Dr. Moore).

AMA Arch Surg. 1957;75(4):598-604. doi:10.1001/archsurg.1957.01280160108014

Introduction  It is becoming increasingly difficult to sustain, or even acquire, a reasonably hopeful attitude toward the problem of carcinoma of the breast. The value of "early diagnosis" as a basis for hope has been discounted by authors who have branded it a "shibboleth" we ought to discard. The impressive evidence presented by MacDonald,7 McKinnon,9 and Park and Lees,10 and others, stimulated us to study the cases of carcinoma of the breast at the Louisville General Hospital, a series which is well adapted to a controlled, retrospective clinical study. An earlier series (Shaw12), from 1934 to 1944, was re-reviewed and compared with a new series of cases, from 1945 to 1951. Unexpectedly, we found a notable increase in five-year survivals in the second series as compared with the first, and we have tried to find the reason for it.

Material and Results  Two hundred sixty consecutive

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