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December 1957

Studies on Hypothermia in Abdominal Surgery: II. Occlusion of the Vascular Inflow to the Liver

Author Affiliations

From the Department of Experimental Surgery, McGill University Faculty of Medicine.

AMA Arch Surg. 1957;75(6):1011-1019. doi:10.1001/archsurg.1957.01280180143022

The successful application of hypothermia to the surgery of the heart and brain is too well known to call for extensive documentation. Our own studies, which began with the extension of the safe time of occlusion of the abdominal aorta by means of hypothermia, reported in Part I,1 have been extended to the specific devascularization of the liver. These latter experiments will be reported here.

Resections of the liver in normothermic patients have been successfully accomplished by several surgeons. The largest series appears to be the four patients reported by Pack and colleagues.2 The hazard of extensive blood loss, and of serious bile leakage owing to failure of complete bile-duct ligature in a sanguineous field, have kept these operations from gaining general acceptance. Bernhard and colleagues3 have reported experiments similar to ours which indicate that a significant increase in safe operating time may be achieved by the

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