Despite the abundance of smooth muscle found within the tracheobronchial tree, primary muscle tumors within the lung are rare, as evidenced by the paucity of reports documenting such tumors.Forkel2 recognized a fibromyoma of the lung in a necropsy specimen and reported this finding in 1909. Neumann7 reported instances of leiomyosarcoma in the lung in autopsy studies in 1938. The first antemortem diagnosis of pulmonary leiomyosarcoma was reported by Randall and Blades8 in 1946. Their patient complained of hemoptysis and dyspnea. A positive biopsy specimen was obtained during bronchoscopy. Both benign and malignant muscle tumors arising in the lung have been reported sporadically during the last 10 years. Although the total number of leiomyosarcomas of the lung reported to date is small, a survey of the experience with malignancies of this type might reveal certain facts which could serve as a basis for the management of
HEWLETT TH, McCARTY JE. Pulmonary Leiomyosarcoma: Review and Report of a Case. AMA Arch Surg. 1958;76(1):81–86. doi:10.1001/archsurg.1958.01280190083015
Monkeypox Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.