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February 1958

Laboratory Studies in the Evaluation of Postphlebitic Disease

Author Affiliations

Durham, N. C.
From the Departments of Surgery and Radiology, Duke University School of Medicine, and the Veterans' Administration Hospital.

AMA Arch Surg. 1958;76(2):228-238. doi:10.1001/archsurg.1958.01280200050006

The purpose of this paper is to describe our experience with three tests in the evaluation of patients with postphlebitic limbs. Clinical signs and symptoms have mainly been relied upon in the study of these patients. Our work suggests that these three laboratory tests may be of value in helping (1) to determine the degree of deep venous occlusion, (2) to differentiate between primary varicose veins and postphlebitic incompetent superficial collaterals, and (3) to gain some idea of the efficacy of certain surgical procedures employed in the management of postphlebitic ulcers.

The three tests used are (1) isoflow venography, to obtain a picture of the anatomic derangement and degree of deep venous occlusion; (2) venous pressure studies, to evaluate the functional capacity of the venous valves during exercise and the changes in pressure following venous ligations, and (3) radioactive isotope outflow studies, to study the flow of a small column

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