The Latin verb sequestrare means to separate. The noun sequestrum has well-known orthopedic connotations and is defined in Stedman's "Medical Dictionary" as "a piece of necrosed bone which has become separated from the surrounding healthy osseous tissue." Pryce, in 1946, applied the term to a type of pulmonary pathology wherein the blood supply of a bronchopulmonary segment is derived from the aorta rather than the pulmonary artery. This bronchopulmonary mass could be enveloped by lung (intrapulmonary sequestration) or could exist outside an otherwise normal lung (extrapulmonary sequestration). In either case the idea of necrosis is not implied. There is a loss of bronchial connection (unless infection has caused erosion into a bronchus),8 and a variable venous drainage exists in that blood may return via either pulmonary or systemic veins. An excellent review of the differences between intra- and extrapulmonary sequestration, as well as an explanation of the origin of
BERMAN EJ. Extralobar (Diaphragmatic) Sequestration of the Lung. AMA Arch Surg. 1958;76(5):724–731. doi:10.1001/archsurg.1958.01280230064009
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