A statistical review of cases, in general, is attended with little difficulty, and the author, after completing a series, is usually contented with his findings. But it is indeed a difficult matter when one attempts to make a study of malignant diseases of the gallbladder, liver, and biliary tract. This is due primarily to the final diagnosis, placed upon the chart and recorded in the record room, many of the cases being tabulated from a clinical angle, often without waiting for the receipt of a final microscopic examination; others bearing a different microscopic interpretation on the part of the pathologist.
Four hundred eighty-eight case histories have been reviewed; all have been classified under "malignant disease of the gallbladder, liver, and biliary tract." Of these, 52 cases of primary carcinoma of the gallbladder have been noted, 48 appearing in the Albany Hospital between the years 1935 and 1957, inclusive, and 4
J. L. DONHAUSER. Primary Carcinoma of the GallbladderAn Analysis of Fifty-Two Cases. AMA Arch Surg. 1958;77(6):918–924. doi:10.1001/archsurg.1958.01290050088017