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December 1958

Bronchogenic Carcinoma: Importance of the Cell Type

Author Affiliations

From the Department of Surgery, The Johns Hopkins University School of Medicine and The Johns Hopkins Hospital.

AMA Arch Surg. 1958;77(6):925-932. doi:10.1001/archsurg.1958.01290050095018

Introduction  A greater number of cases of bronchogenic carcinoma are seen today than in the past. Whether this increase in frequency is real, or only seeming, is not definitely known, but more important is the fact that this disease presents a serious problem and is now relatively common. It is, therefore, imperative that all factors affecting treatment and prognosis be thoroughly evaluated. Although there have been many studies made and figures compiled of bronchogenic carcinoma, relatively few concerning the individual cell type have been reported. In the treatment of most tumors, one of the factors concerning the ultimate prognosis of the disease is its cell type. With bronchogenic carcinoma, however, the studies concerning individual cell types, although relatively few, have been largely controversial.Many authors hold the view that the cell type is a highly valuable prognostic element.1-4 Koletsky,5 in 1938, in his correlation of the clinical course

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