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September 1959

Implants of the Internal Mammary Artery into Ischemic Dog Ventricles

Author Affiliations

San Francisco With the Technical Assistance of Beryl Kallemeyn, R.N.
From the Surgical Research Unit, Department of Surgery, Mount Zion Hospital. This project has been supported by grants-in-aid from the National Heart Institute of the Department of Health, Education, and Welfare of the United States and by the Louis Brownstone Memorial Fund.

AMA Arch Surg. 1959;79(3):497-499. doi:10.1001/archsurg.1959.04320090145022

Implantation of the internal mammary artery into the ventricular myocardium as proposed by Vineberg, has been under study in our laboratory for the past three and one-half years. In a previous article, We have reported our experiences with this procedure as applied to normal dog ventricles.5 We used a technique in which, among other details, all the branches of the internal mammary artery were ligated and cut, the end of the main artery was left open in the myocardial tunnel, and the implant was anchored to the epicardium at the tunnel entrance. A description of this technique is reported elsewhere.3,4

In our first series of 30 implants into 16 normal (nonischemic) dog ventricles, subjected to second operation 4-28 months later, we found no evidence that the implant afforded protection against acute graded coronary artery ligations. At time of killing, injection of Schlesinger mass into the heart side of the